Picoliter Single-Cell Reactor for Proteome Profiling by In Situ Cell Lysis, Protein Immobilization, Digestion, and Droplet Transfer.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.4c00117
Abstract: Global profiling of single-cell proteomes can reveal cellular heterogeneity, thus benefiting precision medicine. However, current mass spectrometry (MS)-based single-cell proteomic sample processing still faces technical challenges associated with processing efficiency and protein recovery. Herein, we… read more here.
Keywords: picoscr; picoliter single; single cell; cell reactor ... See more keywords