Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103258
Abstract: Alzheimer disease (AD), a prevalent neurodegenerative disorder, is one of the leading causes of dementia. However, there is no effective drug for this disease to date. Picrasma quassioides (D.Don) Benn, a Chinese traditional medicine, was… read more here.
Keywords: picrasma quassioides; active constituents; effects picrasma; alzheimer disease ... See more keywords
Bioactivity-guided isolation of β-Carboline alkaloids with potential anti-hepatoma effect from Picrasma quassioides (D. Don) Benn.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.08.004
Abstract: β-Carboline alkaloids in Picrasma quassioides (D. Don) Benn. have been proven to possess inhibitory activity against various cancer cells. However, their effect on hepatocellular carcinoma and structure-activity relationships (SAR) have not been systematically reported. In… read more here.
Keywords: picrasma quassioides; bioactivity; quassioides benn; effect ... See more keywords
Picraquanines A－C, three new phenolic derivatives from the stems of Picrasma quassioides.
Sign Up to like & getrecommendations! Published in 2020 at "Natural product research"
DOI: 10.1080/14786419.2020.1727475
Abstract: Three new phenolic derivatives, picraquanines A-C (1-3), along with 6 known ones 4-9 were obtained from the stems of Picrasma quassioides (D. Don) Benn. The new structures were determined by extensive spectroscopic data analysis, including… read more here.
Keywords: new phenolic; picrasma quassioides; picraquanines three; three new ... See more keywords
Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways
Sign Up to like & getrecommendations! Published in 2021 at "Oncology Reports"
DOI: 10.3892/or.2021.8117
Abstract: Nasopharyngeal carcinoma (NPC) is an indicator disease in Asia due to its unique geographical and ethnic distribution. Dehydrocrenatidine (DC) is a β-carboline alkaloid abundantly present in Picrasma quassioides (D. Don) Benn, a deciduous shrub or… read more here.
Keywords: jnk erk; human npc; picrasma quassioides; apoptosis ... See more keywords