Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation.
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DOI: 10.1016/j.celrep.2019.05.076
Abstract: piRNAs play significant roles in suppressing transposons and nonself nucleic acids, maintaining genome integrity, and defending against viral infections. In C. elegans, piRNA precursors are transcribed in the nucleus and are subjected to a number of… read more here.
Keywords: pics complex; maturation; functional proteomics; chromosome segregation ... See more keywords