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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13414-9
Abstract: Pif1 plays multiple roles in maintaining genome stability and preferentially unwinds forked dsDNA, but the mechanism by which Pif1 unwinds forked dsDNA remains elusive. Here we report the structure of Bacteroides sp Pif1 (BaPif1) in…
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Keywords:
dsdna two;
forked dsdna;
unwinds forked;
bapif1 ... See more keywords
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1
Published in 2017 at "Biochemical Society transactions"
DOI: 10.1042/bst20170096
Abstract: Pif1 family helicases have multiple roles in the maintenance of nuclear and mitochondrial DNA in eukaryotes. Saccharomyces cerevisiae Pif1 is involved in replication through barriers to replication, such as G-quadruplexes and protein blocks, and reduces…
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Keywords:
function pif1;
helicase;
pif1 helicase;
pif1 ... See more keywords
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Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab232
Abstract: Abstract Meiotic recombination ensures proper chromosome segregation to form viable gametes and results in gene conversions events between homologs. Conversion tracts are shorter in meiosis than in mitotically dividing cells. This results at least in…
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Keywords:
conversion;
helicase;
meiotic recombination;
recombination ... See more keywords
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1
Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1058040
Abstract: Background: Petite Integration Factor 1 (PIF1) is a multifunctional helicase and DNA processing enzyme that plays an important role in the process of several cancer types. However, the relationship between clear cell renal cell carcinoma…
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Keywords:
cell;
ccrcc;
expression pif1;
pif1 ... See more keywords