Direct administration of 2-Hydroxypropyl-Beta-Cyclodextrin into guinea pig cochleae: Effects on physiological and histological measurements
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DOI: 10.1371/journal.pone.0175236
Abstract: 2-Hydroxypropyl-Beta-Cyclodextrin (HPβCD) can be used to treat Niemann-Pick type C disease, Alzheimer’s disease, and atherosclerosis. But, a consequence is that HPβCD can cause hearing loss. HPβCD was recently found to be toxic to outer hair… read more here.
Keywords: guinea pig; cyclodextrin; hydroxypropyl beta; pig cochleae ... See more keywords