Interspecies Variation Affects Islet Amyloid Polypeptide Membrane Binding.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.3c00005
Abstract: The aggregation of islet amyloid polypeptide (IAPP) is associated with β-cell dysfunction in type 2 diabetes (T2D) in humans. One possible mechanism of toxicity is the interaction of IAPP oligomers with lipid membranes to disrupt… read more here.
Keywords: pig iapp; iapp; amyloid polypeptide; membrane ... See more keywords