“You cannot stay in the laboratory forever”*: Taking pig kidney xenotransplantation from the laboratory to the clinic
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103562
Abstract: Progress in life-supporting kidney transplantation in the genetically-engineered pig-to-nonhuman primate model has been encouraging, with pig kidneys sometimes supporting life for > 1 year. What steps need to be taken by (i) the laboratory team,… read more here.
Keywords: pig kidney; stay laboratory; xenotransplantation; laboratory forever ... See more keywords
Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts
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DOI: 10.1111/xen.12795
Abstract: With pig kidney xenotransplantation nearing clinical reality, it is imperative to measure pig kidney function in the graft recipients. Our aims were (i) to compare inulin clearance after a short intravenous (IV) bolus with steady‐state… read more here.
Keywords: glomerular filtration; pig kidney; kidney; inulin ... See more keywords
Decellularized Pig Kidney with a Micro-Nano Secondary Structure Contributes to Tumor Progression in 3D Tumor Model
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DOI: 10.3390/ma15051935
Abstract: In spite of many anti-cancer drugs utilized in clinical treatment, cancer is still one of the diseases with the highest morbidity and mortality worldwide, owing to the complexity and heterogeneity of the tumor microenvironment. Compared… read more here.
Keywords: tumor; tumor model; cell; pig kidney ... See more keywords