Biotransformation of NSAIDs by pig liver microsomes in vitro: Kinetics, metabolites identification and toxicity prediction.
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DOI: 10.1016/j.chemosphere.2017.08.026
Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used pharmaceuticals in animals. In the current study, the biotransformation of five NSAIDs by pig liver microsomes (PLMs) was studied. The pseudo-first-order kinetics mode was… read more here.
Keywords: pig liver; nsaids pig; toxicity; biotransformation nsaids ... See more keywords
Effects of Chinese wolfberry and Astragalus extract on the antioxidant capacity of Tibetan pig liver
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DOI: 10.1371/journal.pone.0245749
Abstract: The objective of this study is to determine the effect of Chinese wolfberry (Lycium barbarum) and Astragalus (Astragalus membranaceus) extract (WAE) on the antioxidant capacity of Tibetan pig liver, and discussed the regulatory effect of… read more here.
Keywords: pig liver; capacity; group; liver ... See more keywords
RNA-Sequencing Characterization of lncRNA and mRNA Functions in Septic Pig Liver Injury
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DOI: 10.3390/genes14040945
Abstract: We assessed differentially expressed (DE) mRNAs and lncRNAs in the liver of septic pigs to explore the key factors regulating lipopolysaccharide (LPS)-induced liver injury. We identified 543 DE lncRNAs and 3642 DE mRNAs responsive to… read more here.
Keywords: injury; liver injury; pig liver; protein ... See more keywords