Porcine reproductive and respiratory syndrome virus (PRRSV) non-structural protein (NSP)1 transcriptionally inhibits CCN1 and CCN2 expression by blocking ERK-AP-1 axis in pig macrophages in vitro.
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DOI: 10.1016/j.rvsc.2020.07.029
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is a causative pathogen of PRRS that has generated a serious adverse impact on current global pork production. PRRSV primarily infects pig alveolar macrophages, but poor induction of… read more here.
Keywords: protein; ccn1 ccn2; pig macrophages; blocking erk ... See more keywords