Articles with "pik3ca aberrated" as a keyword



Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

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Published in 2024 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13761

Abstract: Phosphatidylinositol‐4,5‐bisphosphate 3‐kinase catalytic subunit alpha [PIK3CA, encoding PI3Kalpha (also known as p110α)] is one of the most commonly aberrated genes in human cancers. In serous ovarian cancer, PIK3CA amplification is highly frequent but PIK3CA point… read more here.

Keywords: p110; pik3ca aberrated; ovarian cancer; pik3ca ... See more keywords