The Prognostic Value of PIK3CA Copy Number Gain in Penile Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Urology"
DOI: 10.1016/j.urology.2018.03.056
Abstract: OBJECTIVE To determine whether phosphatidylinositol-4,5-bisphosphate 3- kinase, catalytic subunit alpha (PIK3CA) copy number gain in penile cancer has prognostic value and association with histopathological parameters, human papillomavirus (HPV), and clinical outcome. METHODS PIK3CA copy number… read more here.
Keywords: copy number; number gain; pik3ca copy; cancer ... See more keywords
PIK3CA copy number gain and inhibitors of the PI3K/AKT/mTOR pathway in triple-negative breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor molecular case studies"
DOI: 10.1101/mcs.a006255
Abstract: As wider insights are gained on the molecular landscape of triple-negative breast cancer (TNBC), novel targeted therapeutic strategies might become an option in this setting as well. Activating mutations of PIK3CA represent the second most… read more here.
Keywords: pi3k akt; pik3ca copy; akt mtor; mtor pathway ... See more keywords