PIK3CB promotes oesophageal cancer proliferation through the PI3K/AKT/mTOR signalling axis
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DOI: 10.1002/cbin.11847
Abstract: PIK3CB is abnormally expressed in various carcinomas and affects the proliferation, invasion and drug resistance of cancer cells. However, its role in oesophageal squamous cell carcinoma (ESCC) is still unclear. In this study, PIK3CB was… read more here.
Keywords: mtor signalling; pi3k akt; escc; pik3cb ... See more keywords
LukS-PV Induces Apoptosis via the SET8-H4K20me1-PIK3CB Axis in Human Acute Myeloid Leukemia Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.718791
Abstract: Evidence suggests that histone modification disorders are involved in leukemia pathogenesis. We previously reported that LukS-PV, a component of Panton–Valentine leukocidin (PVL), has antileukemia activities that can induce differentiation, increase apoptosis, and inhibit proliferation of… read more here.
Keywords: apoptosis; myeloid leukemia; pik3cb; h4k20me1 ... See more keywords