PIK3CB/p110&bgr; is a selective survival factor for glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-Oncology"
DOI: 10.1093/neuonc/nox181
Abstract: Background Glioblastoma (GBM) is difficult to treat. Phosphoinositide 3-kinase (PI3K) is an attractive therapeutic target for GBM; however, targeting this pathway to effectively treat GBM is not successful because the roles of PI3K isoforms remain… read more here.
Keywords: pi3k isoforms; gbm; p110; pik3cb p110 ... See more keywords
Abstract A15: The selective role of PIK3CB/p110β in temozolomide resistance in glioblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.pi3k-mtor18-a15
Abstract: Background: The divergent roles of phosphatidylinositide 3-kinase (PI3K) family genes in cancer pathogenesis and progression have been highly studied. PI3K genes are divided into three classes (I, II, and III). Class IA PI3K includes three… read more here.
Keywords: p110; pik3cb p110; resistance; pi3k ... See more keywords