Citral Effects on the Expression Profile of Brain-Derived Neurotrophic Factor and Inflammatory Cytokines in Status Epilepticus-Induced Rats Using the Lithium-Pilocarpine Model.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal food"
DOI: 10.1089/jmf.2020.0073
Abstract: Epilepsy is one of the most common neurological disorders. About one-third of people with epilepsy are refractory to available treatments. Studies suggest that mechanisms linked to the immune response and inflammatory process are related to… read more here.
Keywords: pilocarpine model; epilepticus induced; status epilepticus; inflammatory ... See more keywords
Optogenetic activation of the superior colliculus attenuates spontaneous seizures in the pilocarpine model of temporal lobe epilepsy
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DOI: 10.1111/epi.17469
Abstract: Decades of studies have indicated that activation of the deep and intermediate layers of the superior colliculus can suppress seizures in a wide range of experimental models of epilepsy. However, prior studies have not examined… read more here.
Keywords: optogenetic activation; activation superior; model temporal; superior colliculus ... See more keywords
Early morphological and functional changes in the GABAergic system of hippocampus in the rat lithium-pilocarpine model of epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biological Sciences"
DOI: 10.1134/s0012496617010045
Abstract: We studied early alterations in the GABAergic system of the rat hippocampus in the lithium–pilocarpine model of epilepsy. Twenty-four hours after the pilocarpine treatment, a decrease in the number of calretinin-positive interneurons was observed in… read more here.
Keywords: gabaergic system; pilocarpine model; lithium pilocarpine; rat ... See more keywords
Effects of dexamethasone on the Li-pilocarpine model of epilepsy: protection against hippocampal inflammation and astrogliosis
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DOI: 10.1186/s12974-018-1109-5
Abstract: BackgroundTemporal lobe epilepsy (TLE) is the most common form of partial epilepsy and is accompanied, in one third of cases, by resistance to antiepileptic drugs (AED). Most AED target neuronal activity modulated by ionic channels,… read more here.
Keywords: epilepsy; secretion; pilocarpine model; model ... See more keywords
Differences in Evolution of Epileptic Seizures and Topographical Distribution of Tissue Damage in Selected Limbic Structures Between Male and Female Rats Submitted to the Pilocarpine Model
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DOI: 10.3389/fneur.2022.802587
Abstract: Epidemiological evidence shows that clinical features and comorbidities in temporal lobe epilepsy (TLE) may have different manifestations depending on the sex of patients. However, little is known about how sex-related mechanisms can interfere with the… read more here.
Keywords: pilocarpine model; female rats; male female; epileptic seizures ... See more keywords