Pilose antler peptide protects osteoblasts from inflammatory and oxidative injury through EGF/EGFR signaling.
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DOI: 10.1016/j.ijbiomac.2017.02.056
Abstract: Epidermal growth factor (EGF)/EFG receptor (EGFR) signaling plays an important role in the osteoblastogenesis. The potential effects of pilose antler peptide (PAP) on osteoblast cell damages was investigated in our present study through EGF/EGFR signaling.… read more here.
Keywords: pilose antler; factor; egfr signaling; egf egfr ... See more keywords
Mechanism of Pilose Antler in Treatment of Osteoporosis Based on Network Pharmacology
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DOI: 10.1155/2022/5298892
Abstract: Background The purpose of this study was to demonstrate the pharmacodynamic material basis and molecular mechanism of pilose antler (PA) in the prevention and treatment of osteoporosis (OP) by the method of network pharmacology. Methods… read more here.
Keywords: network; treatment osteoporosis; pharmacology; pilose antler ... See more keywords
Pilose antler (Cervus elaphus Linnaeus) polysaccharide and polypeptide extract inhibits bone resorption in high turnover type osteoporosis by stimulating the MAKP and MMP-9 signaling pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4209040
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Pilose antler is a traditional Chinese medicine used to improve kidney function, strengthen tendons and bones, and prolong life, among other uses. It is widely employed in the treatment of osteoporosis. However, the… read more here.
Keywords: high turnover; osteoporosis; pilose antler; mmp ... See more keywords
The Protective Effect of Pilose Antler Peptide on CUMS-Induced Depression Through AMPK/Sirt1/NF-κB/NLRP3-Mediated Pyroptosis
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DOI: 10.3389/fphar.2022.815413
Abstract: Background: Pilose antler peptide (PAP), prepared from the pilose antler of Cervus nippon Temminck, is widely used in traditional Chinese medicine (TCM) against various inflammatory disorders. TCM prescriptions containing pilose antler are often prescribed clinically… read more here.
Keywords: effect; ampk sirt1; depression; pilose antler ... See more keywords