Obstruction of pilus retraction stimulates bacterial surface sensing
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aan5706
Abstract: Elucidating a bacterial sense of touch Bacteria can adhere to surfaces within the host. This leads to tissue colonization, induction of virulence, and eventually the formation of biofilms—multicellular bacterial communities that resist antibiotics and clearance… read more here.
Keywords: pili; surface; pilus retraction; surface sensing ... See more keywords
Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009299
Abstract: Neisseria meningitidis (the meningococcus) remains a major cause of bacterial meningitis and fatal sepsis. This commensal bacterium of the human nasopharynx can cause invasive diseases when it leaves its niche and reaches the bloodstream. Blood-borne… read more here.
Keywords: sepsis; sustained bacteremia; pilus retraction; outcome meningococcal ... See more keywords