Structures of the Escherichia coli type 1 pilus during pilus rod assembly and after assembly termination
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DOI: 10.1038/s41467-025-60325-z
Abstract: Uropathogenic Escherichia coli strains use filamentous type 1 pili to adhere to and invade uroepithelial cells. The pilus consists of a flexible tip fibrillum, formed by the adhesin FimH and the subunits FimG and FimF.… read more here.
Keywords: assembly termination; type pilus; pilus rod; pilus ... See more keywords
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
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DOI: 10.7554/elife.31662
Abstract: Uropathogenic E. coli (UPEC), which cause urinary tract infections (UTI), utilize type 1 pili, a chaperone usher pathway (CUP) pilus, to cause UTI and colonize the gut. The pilus rod, comprised of repeating FimA subunits,… read more here.
Keywords: pilus; pilus rod; type pilus; functional role ... See more keywords