Proto-oncogene serine/threonine kinase PIM3 promotes cell migration via modulating Rho GTPase signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00821
Abstract: The proto-oncogene serine/threonine-protein kinase PIM3 plays critical roles in cancer, and it has been extensively exploited as a drug target. Here we investigated the quantitative changes in the cellular proteome and phosphoproteome in liver cancer… read more here.
Keywords: pim3; cell migration; proto oncogene; rho gtpase ... See more keywords
Multicenter validation of PIM3 and PIM2 in Brazilian pediatric intensive care units
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.1036007
Abstract: Objective To validate the PIM3 score in Brazilian PICUs and compare its performance with the PIM2. Methods Observational, retrospective, multicenter study, including patients younger than 16 years old admitted consecutively from October 2013 to September… read more here.
Keywords: pim3; calibration; mortality; risk ... See more keywords