Effect of gold nanoparticles on the structure and neuroprotective function of protein L-isoaspartyl methyltransferase (PIMT)
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DOI: 10.1038/s41598-021-93752-1
Abstract: Fibrillation of peptides and proteins is implicated in various neurodegenerative diseases and is a global concern. Aging leads to the formation of abnormal isoaspartate (isoAsp) residues from isomerization of normal aspartates in proteins, triggering fibril… read more here.
Keywords: protein isoaspartyl; methyltransferase; pimt; methyltransferase pimt ... See more keywords
PIMT Controls Insulin Synthesis and Secretion through PDX1
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DOI: 10.3390/ijms24098084
Abstract: Pancreatic beta cell function is an important component of glucose homeostasis. Here, we investigated the function of PIMT (PRIP-interacting protein with methyl transferase domain), a transcriptional co-activator binding protein, in the pancreatic beta cells. We… read more here.
Keywords: pimt; beta; secretion; insulin ... See more keywords