Etherification of Fluoroarenes with Alkoxyboronic Acid Pinacol Esters via C-F Bond Cleavage.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01864
Abstract: Potassium-base-mediated defluoroetherification of aryl and heteroaryl fluorides with alkoxyboronic acid pinacol esters under transition-metal-free conditions is reported. This protocol efficiently and safely provides a wide variety of aryl ethers in high yields without using metal… read more here.
Keywords: pinacol esters; cleavage; alkoxyboronic acid; acid pinacol ... See more keywords
Alkyl Radical Generation from Alkylboronic Pinacol Esters through Substitution with Aminyl Radicals.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c01129
Abstract: Alkylboronic pinacol esters (APEs) are highly versatile reagents in organic synthesis. However, the direct generation of alkyl radicals from commonly used, bench-stable APEs has not been well explored. In this communication, alkyl radical generation from… read more here.
Keywords: alkyl radical; pinacol esters; alkylboronic pinacol; generation ... See more keywords