Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules
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DOI: 10.1021/acscentsci.3c00015
Abstract: Nature has evolved intricate machinery to target and degrade RNA, and some of these molecular mechanisms can be adapted for therapeutic use. Small interfering RNAs and RNase H-inducing oligonucleotides have yielded therapeutic agents against diseases… read more here.
Keywords: proximity induced; pinad; degrader; small molecules ... See more keywords