Articles with "pio" as a keyword



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Interpreting the Palu’e Legend Pio Pikariwu

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Published in 2023 at "Indonesia and the Malay World"

DOI: 10.1080/13639811.2023.2172874

Abstract: ABSTRACT This article explores the Palu’e legend Pio pikariwu and how the main character Pio is contested by two traditionally rival politico-ceremonial domains on Palu’e island. The stateless clan-structured societies of eastern Indonesia, such as… read more here.

Keywords: pio; legend pio; pio pikariwu; palu legend ... See more keywords
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PPARγ activation improved learning and memory and attenuated oxidative stress in the hippocampus and cortex of aged rats

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Published in 2022 at "Physiological Reports"

DOI: 10.14814/phy2.15538

Abstract: Oxidative stress has an important role in brain aging and its consequences include cognitive decline and physiological disorders. Peroxisome proliferator‐activated receptor‐γ (PPARγ) activation has been suggested to decrease oxidative stress. In the current research, the… read more here.

Keywords: stress; pio; oxidative stress; ppar activation ... See more keywords
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Pioglitazone Protects Against Hypoxia-Induced Cardiomyocyte Apoptosis Through Inhibiting NLRP3/Caspase-1 Pathway in vivo and in vitro.

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Published in 2022 at "International heart journal"

DOI: 10.1536/ihj.21-404

Abstract: This study aims to explore the underlying mechanisms of how Pioglitazone (Pio) affects myocardial ischemia-reperfusion (I/R) injury. In this study, after pretreatment of Pio, the pathologic change of myocardial tissues was measured via hematoxylin and… read more here.

Keywords: nlrp3 caspase; apoptosis; pio; caspase pathway ... See more keywords
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223-OR: Pioglitazone Discontinuation in Patients with Nonalcoholic Steatohepatitis (NASH) Is Associated with Disease Recurrence

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Published in 2019 at "Diabetes"

DOI: 10.2337/db19-223-or

Abstract: Pioglitazone (PIO) therapy results in a ∼60% resolution of NASH in patients with prediabetes or T2DM. However, the effects of treatment discontinuation have not been carefully examined. To this end, we assessed plasma aminotransferases (LFTs)… read more here.

Keywords: none; pio; recurrence; pioglitazone ... See more keywords
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Effects of PPARγ agonist pioglitazone on cardiac fibrosis in diabetic mice by regulating PTEN/AKT/FAK pathway.

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Published in 2021 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202101_24646

Abstract: OBJECTIVE The aim of this study was to explore the role of pioglitazone (PIO), a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, in cardiac fibrosis of diabetic mice. MATERIALS AND METHODS A total of 60 adult male… read more here.

Keywords: dcm; pio; fak; group ... See more keywords
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Pioglitazone modulates immune activation and ameliorates inflammation induced by injured renal tubular epithelial cells via PPARγ/miRNA‑124/STAT3 signaling

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Published in 2022 at "Biomedical Reports"

DOI: 10.3892/br.2022.1584

Abstract: Acute kidney injury (AKI) is commonly a result of renal ischemia reperfusion injury (IRI), which produces clinical complications characterized by the rapid deterioration of renal function, leading to chronic kidney disease and increases the risk… read more here.

Keywords: mirna 124; ppar; pio; iri ... See more keywords
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Pioglitazone restores the homocysteine-impaired function of endothelial progenitor cells via the inhibition of the protein kinase C/NADPH oxidase pathway

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Published in 2018 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2018.9154

Abstract: Homocysteine (Hcy) has been shown to impair the migratory and adhesive activity of endothelial progenitor cells (EPCs). As a peroxisome proliferator-activated receptor γ agonist, pioglitazone (PIO) has been predicted to regulate angiogenesis, and cell adhesion,… read more here.

Keywords: oxidase; progenitor cells; pio; endothelial progenitor ... See more keywords