An integrated computational pipeline for designing high-affinity nanobodies with expanded genetic codes.
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DOI: 10.1093/bib/bbab338
Abstract: Protein engineering and design principles employing the 20 standard amino acids have been extensively used to achieve stable protein scaffolds and deliver their specific activities. Although this confers some advantages, it often restricts the sequence,… read more here.
Keywords: affinity; nanobody; computational pipeline; integrated computational ... See more keywords