Articles with "pipeline drug" as a keyword



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An in silico–in vitro pipeline for drug cardiotoxicity screening identifies ionic pro‐arrhythmia mechanisms

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Published in 2022 at "British Journal of Pharmacology"

DOI: 10.1111/bph.15915

Abstract: Before advancing to clinical trials, new drugs are screened for their pro‐arrhythmic potential using a method that is overly conservative and provides limited mechanistic insight. The shortcomings of this approach can lead to the mis‐classification… read more here.

Keywords: pipeline drug; vitro pipeline; drug cardiotoxicity; screening identifies ... See more keywords