The "PepSAVI-MS" Pipeline for Natural Product Bioactive Peptide Discovery.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.6b03625
Abstract: The recent increase in extensively drug-resistant bacterial pathogens and the associated increase of morbidity and mortality demonstrate the immediate need for new antibiotic backbones with novel mechanisms of action. Here, we report the development of… read more here.
Keywords: pipeline; bioactive peptide; peptide discovery; pipeline natural ... See more keywords
A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.956154
Abstract: The homeostasis of eukaryotic cells is inseverable of that of the endoplasmic reticulum (ER). The main function of this organelle is the synthesis and folding of a significant portion of cellular proteins, while also being… read more here.
Keywords: molecule inhibitors; endoplasmic reticulum; stress; small molecule ... See more keywords