Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.3219
Abstract: Importance &bgr;-Lactam antibiotics are often coadministered with intravenous (IV) vancomycin hydrochloride for children with suspected serious infections. For adults, the combination of IV vancomycin plus piperacillin sodium/tazobactam sodium is associated with a higher risk of… read more here.
Keywords: bgr lactam; combination; vancomycin plus; piperacillin tazobactam ... See more keywords
Acute kidney injury associated with concomitant vancomycin and piperacillin/tazobactam administration: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "International Urology and Nephrology"
DOI: 10.1007/s11255-018-1870-5
Abstract: BackgroundAs a tricyclic glycopeptide antibiotic used to treat acute infections, Vancomycin (VAN) is often administered with piperacillin/tazobactam (PT) to treat various infections in clinical practice. However, whether the combination of these two drugs, compared to… read more here.
Keywords: piperacillin tazobactam; acute kidney; van; kidney injury ... See more keywords
Population pharmacokinetics of continuous infusion piperacillin/tazobactam in very elderly hospitalized patients and considerations for target attainment against Enterobacterales and Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2021.106408
Abstract: Continuous infusion (CI) piperacillin/tazobactam is frequently used to treat infections in very elderly patients. The aims is to conduct a population pharmacokinetic analysis of CI piperacillin/tazobactam and to identify optimal dosages for safe and effective… read more here.
Keywords: permissible doses; continuous infusion; piperacillin; piperacillin tazobactam ... See more keywords
Comparison of acute kidney injury risk associated with vancomycin and concomitant piperacillin/tazobactam or cefepime in the intensive care unit
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Critical Care"
DOI: 10.1016/j.jcrc.2018.08.007
Abstract: Purpose: The objective of this study was to evaluate AKI incidence with concomitant vancomycin and piperacillin/tazobactam (PTZ) compared to vancomycin and cefepime (FEP) in critically ill patients. Materials and methods: A retrospective, cohort study was… read more here.
Keywords: vancomycin ptz; piperacillin tazobactam; risk; concomitant ... See more keywords
Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-85946-4
Abstract: Effective implementation of antibiotic stewardship, especially in critical care, is limited by a lack of direct comparative investigations on how different antibiotics impact the microbiota and antibiotic resistance rates. We investigated the impact of two… read more here.
Keywords: tazobactam distinct; piperacillin tazobactam; third generation; generation cephalosporins ... See more keywords
Clinical efficacy of piperacillin/tazobactam in the treatment of complicated skin and soft tissue infections
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1341491
Abstract: ABSTRACT Introduction: Complicated skin and soft tissue infections (cSSTIs) are skin and soft tissue infections (SSTIs) that involve deep soft tissue. cSSTIs often require surgical intervention and/or hospitalization. cSSTIs are associated with significant mortality and… read more here.
Keywords: piperacillin tazobactam; treatment; csstis; soft tissue ... See more keywords
SHV Hyperproduction as a Mechanism for Piperacillin-Tazobactam Resistance in Extended-Spectrum Cephalosporin-Susceptible Klebsiella pneumoniae.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial drug resistance"
DOI: 10.1089/mdr.2019.0079
Abstract: This study aimed to determine the mechanism of resistance to piperacillin-tazobactam (TZP) in Klebsiella pneumoniae bloodstream isolates that are susceptible to extended-spectrum cephalosporins (ESCs). Antibiotic susceptibility was determined for K. pneumoniae isolated from children with… read more here.
Keywords: shv; mechanism; tzp; pneumoniae ... See more keywords
Piperacillin/Tazobactam versus Tobramycin-Based Antibiotic Prophylaxis for Type III Open Fractures.
Sign Up to like & getrecommendations! Published in 2019 at "Surgical infections"
DOI: 10.1089/sur.2019.064
Abstract: Background: Type III open fractures are associated with an infection rate as high as 50%. The optimal antibiotic for open fracture prophylaxis remains unclear, and the literature comparing the safety and efficacy of different antibiotic… read more here.
Keywords: group; prophylaxis; piperacillin tazobactam; iii open ... See more keywords
Evaluation of Piperacillin-Tazobactam for Antibiotic Prophylaxis in Traumatic Grade III Open Fractures.
Sign Up to like & getrecommendations! Published in 2021 at "Surgical infections"
DOI: 10.1089/sur.2021.122
Abstract: Background: Broad-spectrum antibiotic agents are sometimes utilized for prophylaxis of Gustilo grade III open fractures. However, this practice is not recommended by current guidelines, and it is unknown how patient outcomes are impacted. This study… read more here.
Keywords: antibiotic prophylaxis; prophylaxis; piperacillin tazobactam; grade iii ... See more keywords
Risk of Acute Kidney Injury in Patients on Concomitant Vancomycin and Piperacillin–Tazobactam Compared to Those on Vancomycin and Cefepime
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/ciw709
Abstract: Background. Recent evidence suggests that among patients receiving vancomycin, receipt of concomitant piperacillin–tazobactam increases the risk of nephrotoxicity. Well-controlled, adequately powered studies comparing rates of acute kidney injury (AKI) among patients receiving vancomycin + piperacillin–tazobactam… read more here.
Keywords: vpt; piperacillin tazobactam; aki; patients receiving ... See more keywords
Predicting Resistance to Piperacillin-Tazobactam, Cefepime and Meropenem in Septic Patients With Bloodstream Infection Due to Gram-Negative Bacteria
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/cix612
Abstract: Background Predicting antimicrobial resistance in gram-negative bacteria (GNB) could balance the need for administering appropriate empiric antibiotics while also minimizing the use of clinically unwarranted broad-spectrum agents. Our objective was to develop a practical prediction… read more here.
Keywords: gram negative; infection; negative bacteria; piperacillin tazobactam ... See more keywords