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   Articles with "piperazine" as a keyword



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Nonconventional Luminescent Piperazine-Containing Hyperbranched Polysiloxanes with Pure n-electron.

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recommendations! Published in 2023 at "Small"

DOI: 10.1002/smll.202302095

Abstract: Nonconventional luminogens with high quantum yield (QY) possess very potential applications in various fields. However, the preparation of such luminogens remains a great challenge. Herein, the first example of piperazine-containing hyperbranched polysiloxane exhibiting blue and… read more here.

Keywords: nonconventional luminescent; piperazine containing; luminescent piperazine; piperazine ... See more keywords
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New phenolic Mannich bases with piperazines and their bioactivities.

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recommendations! Published in 2019 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2019.103057

Abstract: In this study, new Mannich bases, 2-(4-hydroxy-3-methoxy-5-((substitutedpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one (1, 2, 4, 5, 8), 2-(3-((substituted)piperazin-1-yl)methyl)-4-hydroxy-5-methoxybenzylidene)-2,3-dihydro-1H-inden-1-one (3, 6, 7) were synthesized with the reaction of vanilin derived chalcone compound (2-(4-hydroxy-3-methoxybenzylidene)indan-1-one), paraformaldehyde and suitable amine in 1:1.2:1 mol ratios.… read more here.

Keywords: new phenolic; phenolic mannich; bases piperazines; mannich bases ... See more keywords
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Effect of the alkyl group in the piperazine N-substitution on the therapeutic action of rifamycins: A drug-membrane interaction study.

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recommendations! Published in 2018 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2018.04.027

Abstract: In this work, we studied the effects of the N-alkyl group (methyl, cyclopentyl) in the piperazine ring of, respectively, rifampicin (RIF) and rifapentine (RPT) to correlate this substitution with their differential pharmacokinetic properties and overall… read more here.

Keywords: alkyl group; group; drug membrane; interaction ... See more keywords
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Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1.

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recommendations! Published in 2021 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2021.113591

Abstract: JNJ4796, a small molecule fuse inhibitor targeting the conserved stem region of hemagglutinin, effectively neutralized a broad spectrum of group 1 influenza A virus (IAV), and protected mice against lethal and sublethal influenza challenge after… read more here.

Keywords: rings jnj4796; sar research; influenza virus; optimization sar ... See more keywords
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Morpholine and piperazine based carboxamide derivatives as corrosion inhibitors of mild steel in HCl medium

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recommendations! Published in 2017 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2017.01.075

Abstract: Abstract N -(2-chloroethyl)morpholine-4-carboxamide (NCMC), N -(2-chloroethyl)tiomorpholine-4-carboxamide (NCTC) and N , N -bis(2-chloroethyl)piperazine-1,4-dicarboxamide (NCPD) were studied as corrosion inhibitors for mild steel using atomic absorption spectroscopy (AAS) and gravimetry and thermometry. Results obtained from the three… read more here.

Keywords: mild steel; corrosion inhibitors; inhibitors mild; steel ... See more keywords
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Performance of aqueous tetrabutylammonium hydroxide, piperazine and their blends for carbon dioxide capture

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recommendations! Published in 2018 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2018.06.095

Abstract: Abstract The potential of aqueous ammonium based IL, tetrabutylammonium-hydroxide (TBAOH), the aqueous tertiary amine, piperazine (PZ) and two aqueous solutions of TBAOH and PZ blend for CO2 capturing was estimated by solubility study. For this… read more here.

Keywords: tetrabutylammonium hydroxide; co2 solubility; solubility; piperazine ... See more keywords
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Synthesis and characterization of a new piperazine containing macroacyclic ligand and its Cu(ii) and Co(ii) complexes: An investigation of the ligand's silver specific fluorescent properties

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recommendations! Published in 2021 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2021.130024

Abstract: Abstract A new Schiff base ligand (H2L) was designed and synthesized by the condensation of 2,2′-(piperazine-1,4-diyl)dianiline and 2-hydroxy-3-methoxybenzaldehyde. The copper(II) and cobalt(II) complexes were synthesized by direct reaction the metal ions and the ligand in… read more here.

Keywords: synthesis characterization; silver; ligand; new piperazine ... See more keywords
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The Role of Hydrogen-Bond Between Piperazine and Fullerene Molecules in Stabilizing Polymer:Fullerene Solar Cell Performance.

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recommendations! Published in 2020 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.9b23366

Abstract: Piperazine was recently reported as stabilizer for polymer:fullerene solar cells that can minimize the "burn-in" degradation of the cell. In this paper, the influence of N-substituents on the stabilization effect of piperazine in P3HT:PC61BM cells… read more here.

Keywords: bond; fullerene; pc61bm; performance ... See more keywords
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An antibacterial and biocompatible piperazine polymer

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recommendations! Published in 2019 at "RSC Advances"

DOI: 10.1039/c9ra02219h

Abstract: A novel piperazine polymer (PE), which was prepared through a simple and green method, exhibited good antibacterial activity against E. coli and S. aureus. read more here.

Keywords: biocompatible piperazine; piperazine polymer; piperazine; antibacterial biocompatible ... See more keywords
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PROTACs bearing piperazine-containing linkers: what effect on their protonation state?

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recommendations! Published in 2022 at "RSC Advances"

DOI: 10.1039/d2ra03761k

Abstract: Proteolysis targeting chimeras (PROTACs) represent an emerging class of compounds for innovative therapeutic application. Their bifunctional nature induces the formation of a ternary complex (target protein/PROTAC/E3 ligase) which allows target protein ubiquitination and subsequent proteasomal-dependent… read more here.

Keywords: containing linkers; effect; piperazine containing; protonation ... See more keywords
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Oxidative and genotoxic effect of piperazine on Galleria mellonella (Lepidoptera: Pyralidae) hemolymph.

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recommendations! Published in 2023 at "Environmental entomology"

DOI: 10.1093/ee/nvad028

Abstract: Recently, there are many studies suggesting antibacterial, antifungal, and anthelmintic agents as alternative chemicals to insecticides. In this study, the oxidative and genotoxic effect of Piperazine, a clinically important hexahydropyrazine anthelmintic, on Galleria mellonella L.… read more here.

Keywords: galleria mellonella; piperazine; oxidative genotoxic; hemolymph ... See more keywords