A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines
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DOI: 10.3390/molecules27113419
Abstract: We report a short synthetic route for synthesizing 2,3-substituted piperazine acetic acid esters. Optically pure amino acids were efficiently converted into 1,2-diamines that could be utilized to deliver the title 2,3-substituted piperazines in five steps… read more here.
Keywords: piperazine acetic; concise synthetic; acid esters; acetic acid ... See more keywords