Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16010083
Abstract: Monoamine oxidase-B (MAO-B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) have been considered target enzymes of depression and neurodegenerative diseases, including Alzheimer’s disease (AD). In this study, seventeen N-methyl-piperazine chalcones were synthesized, and their inhibitory activities were… read more here.
Keywords: piperazine chalcones; mao; methyl piperazine; ache ... See more keywords