Piperazine‐Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200385
Abstract: Ketoconazole (KTZ) is an imidazole drug applied topically to treat numerous skin infections. However, as a systemic antifungal, KTZ′ efficacy and safety no longer justify its use as a first‐line treatment. Azole conjugates often display… read more here.
Keywords: piperazine modified; modified ketoconazole; show increased; derivatives show ... See more keywords
A target analyte induced fluorescence band shift of piperazine modified carbon quantum dots: a specific visual detection method for oxytetracycline.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc05406e
Abstract: Through the protection/deprotection of one amine group and the amidation reaction, piperazine was used to modify carbon quantum dots (CQDs) and successfully served as a medium to combine oxytetracyclines (OTC) in solution by hydrogen bonding… read more here.
Keywords: detection method; fluorescence; carbon quantum; piperazine modified ... See more keywords