Articles with "piperazines ht6r" as a keyword



Photo by robbie36 from unsplash

1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT6R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity

Sign Up to like & get
recommendations!
Published in 2022 at "Biomolecules"

DOI: 10.3390/biom13010012

Abstract: In addition to the canonical Gs adenylyl cyclase pathway, the serotonin type 6 receptor (5-HT6R) recruits additional signaling pathways that control cognitive function, brain development, and synaptic plasticity in an agonist-dependent and independent manner. Considering… read more here.

Keywords: ht6r; arylsulfonyl isoindol; activity; piperazines ht6r ... See more keywords