Angiogenesis-Inhibitory Piperidine Alkaloids from the Leaves of Microcos paniculata.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00960
Abstract: Eight new 2,6-disubstituted piperidin-3-ol alkaloids (1-8), featuring a C10 unsaturated alkyl side chain, together with three previously reported analogues (9-11) were isolated from the leaves of medicinal plant Microcos paniculata. Their structures and absolute configurations… read more here.
Keywords: microcos paniculata; inhibitory piperidine; piperidine alkaloids; leaves microcos ... See more keywords
Combining bio- and organocatalysis for the synthesis of piperidine alkaloids.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc03865f
Abstract: There is continued interest in developing cascade processes for the synthesis of key chiral building blocks and bioactive natural products (or analogues). Here, we report a hybrid bio-organocatalytic cascade for the synthesis of a small… read more here.
Keywords: bio organocatalysis; organocatalysis synthesis; synthesis; synthesis piperidine ... See more keywords
2,6-Disubstituted Piperidine Alkaloids with Neuroprotective Activity from Hippobroma longiflora
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DOI: 10.1055/a-1903-2663
Abstract: Abstract Three new alkaloids, hipporidine A ( 1 ), hipporidine B ( 2 ), and (−)-lobeline N -oxide ( 3 ), were discovered from the whole plant of Hippobroma longiflora together with five known compounds… read more here.
Keywords: disubstituted piperidine; neuroprotective activity; hippobroma longiflora; alkaloids neuroprotective ... See more keywords