Mechanistic perspectives on piperidine-catalyzed synthesis of 1,5-benzodiazepin-2-ones
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DOI: 10.1016/j.mcat.2020.110774
Abstract: Abstract This work introduced new members to the pharmaceutical family of 1,5-benzodiazepin-2-ones, 2a–e. These compounds were synthesized in moderate yields via the reaction of 1,2-bifunctional substrates (α-cyanocinnamates) with o-phenylenediamine in xylene. The conduction of the… read more here.
Keywords: mechanistic perspectives; catalyzed synthesis; benzodiazepin ones; perspectives piperidine ... See more keywords