Piperlongumine activates Sirtuin1 and improves cognitive function in a murine model of Alzheimer’s disease
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DOI: 10.1016/j.jff.2018.02.002
Abstract: Abstract Sirtuin1 (Sirt1) is an unusual target for aging and aging-associated diseases. During the screening for Sirt1 activators from natural compounds, piperlongumine (PL), one of the major constituents of Piper longum, potently activated the deacetylase… read more here.
Keywords: function murine; sirtuin1 improves; piperlongumine activates; improves cognitive ... See more keywords