Articles with "piperonyl substitution" as a keyword



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N-Piperonyl substitution on aminoquinoline-pyrimidine hybrids: Effect on the antiplasmodial potency.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.03.007

Abstract: A series of 4-aminoquinoline-piperonyl-pyrimidine hybrids were synthesized with the aim of identifying compounds with enhanced antimalarial activity. All the synthesized molecules were evaluated in vitro against cultured Plasmodium falciparum W2 and D6 strains and exhibited potent… read more here.

Keywords: substitution aminoquinoline; aminoquinoline pyrimidine; aminoquinoline; piperonyl substitution ... See more keywords