Articles with "pipx" as a keyword



Structures of the cyanobacterial nitrogen regulators NtcA and PipX complexed to DNA shed light on DNA binding by NtcA and implicate PipX in the recruitment of RNA polymerase

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Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf096

Abstract: Abstract The CRP-FNR (cAMP receptor protein-fumarate/nitrate reductase regulator) superfamily of transcriptional regulators includes the cyanobacterial master regulator NtcA, which orchestrates large responses of cyanobacteria to nitrogen scarcity. NtcA uses as allosteric activator 2-oxoglutarate (2OG), a… read more here.

Keywords: rna polymerase; nitrogen; pipx; dna binding ... See more keywords

Regulatory Connections Between the Cyanobacterial Factor PipX and the Ribosome Assembly GTPase EngA

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Published in 2021 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.781760

Abstract: Cyanobacteria, phototrophic organisms performing oxygenic photosynthesis, must adapt their metabolic processes to important environmental challenges, like those imposed by the succession of days and nights. Not surprisingly, certain regulatory proteins are found exclusively in this… read more here.

Keywords: nitrogen; ribosome assembly; assembly gtpase; gtpase enga ... See more keywords

The PII-NAGK-PipX-NtcA Regulatory Axis of Cyanobacteria: A Tale of Changing Partners, Allosteric Effectors and Non-covalent Interactions

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Published in 2018 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2018.00091

Abstract: PII, a homotrimeric very ancient and highly widespread (bacteria, archaea, plants) key sensor-transducer protein, conveys signals of abundance or poorness of carbon, energy and usable nitrogen, converting these signals into changes in the activities of… read more here.

Keywords: nitrogen; pii pipx; allosteric effectors; pipx ... See more keywords

Analysing the Cyanobacterial PipX Interaction Network Using NanoBiT Complementation in Synechococcus elongatus PCC7942

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms25094702

Abstract: The conserved cyanobacterial protein PipX is part of a complex interaction network with regulators involved in essential processes that include metabolic homeostasis and ribosome assembly. Because PipX interactions depend on the relative levels of their… read more here.

Keywords: interaction network; pipx; synechococcus elongatus;