Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.08.081
Abstract: In Drosophila, the piRNAs that guide germline transposon silencing are produced from heterochromatic clusters marked by the HP1 homolog Rhino. We show that Rhino promotes cluster transcript association with UAP56 and the THO complex, forming… read more here.
Keywords: precursor complexes; pirna precursor; rhino; cluster heterochromatin ... See more keywords
Adaptive Evolution Targets a piRNA Precursor Transcription Network
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DOI: 10.1016/j.celrep.2020.01.109
Abstract: SUMMARY In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recruits TRF2 to… read more here.
Keywords: transcription; canonical transcription; pirna precursor; non canonical ... See more keywords