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   Articles with "pit1" as a keyword



Why Is There No PiT1/SLC20A1 Pathogenic Variants Yet Linked to Primary Familial Brain Calcification?

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recommendations! Published in 2020 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3973

Abstract: We read with interested the article by Couasnay and colleagues reporting a new role for PiT1 protein, independent of its inorganic phosphate (Pi) transport function, in the regulation and homeostasis of the endoplasmic reticulum (ER)… read more here.

Keywords: couasnay colleagues; brain calcification; pit1; gene ... See more keywords

Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features

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recommendations! Published in 2024 at "Acta Neuropathologica"

DOI: 10.1007/s00401-024-02686-1

Abstract: Pituitary neuroendocrine tumors (PitNETs) are classified according to cell lineage, which requires immunohistochemistry for adenohypophyseal hormones and the transcription factors (TFs) PIT1, SF1, and TPIT. According to the current WHO 2022 classification, PitNETs with co-expression… read more here.

Keywords: sf1 expression; dgst pit1; pit1 sf1; pit1 ... See more keywords

Host Cells Upregulate Phosphate Transporter PIT1 to Inhibit Ehrlichia chaffeensis Intracellular Growth

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms25147895

Abstract: Ehrlichia chaffeensis infects and proliferates inside monocytes or macrophages and causes human monocytic ehrlichiosis (HME), an emerging life-threatening tick-borne zoonosis. After internalization, E. chaffeensis resides in specialized membrane-bound inclusions, E. chaffeensis-containing vesicles (ECVs), to evade… read more here.

Keywords: chaffeensis; host; host cells; intracellular growth ... See more keywords

Zinc Deficiency Promotes Calcification in Vascular Smooth Muscle Cells Independent of Alkaline Phosphatase Action and Partly Impacted by Pit1 Upregulation

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recommendations! Published in 2024 at "Nutrients"

DOI: 10.3390/nu16020291

Abstract: Inorganic phosphate (Pi) is a critical determinant of calcification, and its concentration is regulated by alkaline phosphatase (ALP) and Pit1. ALP is a key regulator of osteogenic calcification and acts by modulating local inorganic phosphate… read more here.

Keywords: zinc deficiency; action; calcification; pit1 ... See more keywords

Synchronous pituitary neuroendocrine tumors (PitNETs)/adenomas of triple SF1/PIT1/TPIT cell lineages with multiple hormone expression.

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recommendations! Published in 2025 at "Clinical neuropathology"

DOI: 10.5414/np301630

Abstract: Synchronous multiple pituitary neuroendocrine tumors (PitNETs)/adenomas are rare tumors of the anterior pituitary that are characterized by the expression of more than one pituitary transcription factor. Here, we describe and discuss an unusual case of… read more here.

Keywords: pitnets adenomas; tpit; sf1; expression ... See more keywords