Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features
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DOI: 10.1007/s00401-024-02686-1
Abstract: Pituitary neuroendocrine tumors (PitNETs) are classified according to cell lineage, which requires immunohistochemistry for adenohypophyseal hormones and the transcription factors (TFs) PIT1, SF1, and TPIT. According to the current WHO 2022 classification, PitNETs with co-expression… read more here.
Keywords: sf1 expression; dgst pit1; pit1 sf1; pit1 ... See more keywords
Clinical and Pathological Features of Pit1/SF1 Multilineage Pituitary Neuroendocrine Tumor
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DOI: 10.1227/neu.0000000000002846
Abstract: BACKGROUND AND OBJECTIVES: Lineage-based classification has critical clinical implications in pituitary neuroendocrine tumor (PitNET). As the most prevalent subtype of multilineage PitNET, PitNET originating from both pituitary-specific positive transcription factor 1 (Pit1) and steroidogenic factor-1… read more here.
Keywords: sf1 adenoma; pitnet; pit1 sf1;