Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2023.5661
Abstract: Key Points Question Can pitavastatin reduce noncalcified coronary plaque and inflammatory biomarkers in people with HIV? Findings In this substudy of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) including 611 people with… read more here.
Keywords: pitavastatin coronary; coronary artery; inflammatory biomarkers; people hiv ... See more keywords
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2584
Abstract: This study was designed to assess the quantitative performance of endogenous biomarkers for organic anion transporting polypeptide (OATP) 1B1/1B3‐mediated drug‐drug interactions (DDIs). Ten healthy volunteers orally received OATP1B1/1B3 probe cocktail (0.2 mg pitavastatin, 1 mg… read more here.
Keywords: drug interactions; oatp1b1 1b3; pitavastatin; cysa ... See more keywords
An improved osseointegration of metal implants by pitavastatin loaded multilayer films with osteogenic and angiogenic properties.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.121260
Abstract: An increasing number of works have highlighted the importance of metal implants surface modification in enhancing bone defect healing through the synergistic osteogenesis-angiogenesis regulation. Studies have shown that pitavastatin has the effect of promoting osteogenesis… read more here.
Keywords: osteogenesis angiogenesis; pitavastatin; multilayer films; pitavastatin loaded ... See more keywords
Outcome of pitavastatin versus atorvastatin therapy in patients with hypercholesterolemia at high risk for atherosclerotic cardiovascular disease.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2020.01.006
Abstract: BACKGROUND There has been no report about outcome of pitavastatin versus atorvastatin therapy in high-risk patients with hypercholesterolemia. METHODS Hypercholesterolemic patients with one or more risk factors for atherosclerotic diseases (n = 664, age = 65, male = 54%, diabetes = 76%, primary… read more here.
Keywords: therapy; risk; end point; pitavastatin ... See more keywords
Pitavastatin-loaded bilosomes for oral treatment of hepatocellular carcinoma: a repurposing approach
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2120925
Abstract: Abstract Albeit its established efficacy as an anti-hyperlipidemic agent, pitavastatin (PIT) has been shown to have other various therapeutic effects. One of these effects is the anti-cancer activity against hepatocellular carcinoma (HCC). This effect has… read more here.
Keywords: hepatocellular carcinoma; hcc; pit; loaded bilosomes ... See more keywords
Improvement of endothelial function by pitavastatin: a meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2018.1428560
Abstract: ABSTRACT Objective. Dyslipidemia is commonly associated with endothelial dysfunction and increased cardiovascular risk. Pitavastatin has been shown to reduce total and low-density lipoprotein cholesterol, to increase high-density lipoprotein (HDL)-cholesterol and improve HDL function. Furthermore, several… read more here.
Keywords: endothelial function; analysis; meta analysis; pitavastatin ... See more keywords
Low-density lipoprotein cholesterol targeting with pitavastatin + ezetimibe for patients with acute coronary syndrome and dyslipidaemia: the HIJ-PROPER study, a prospective, open-label, randomized trial
Sign Up to like & getrecommendations! Published in 2017 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehx162
Abstract: Abstract Aims To elucidate the effects of intensive LDL-C lowering treatment with a standard dose of statin and ezetimibe in patients with dyslipidaemia and high risk of coronary events, targeting LDL-C less than 70 mg/dL (1.8 mmol/L),… read more here.
Keywords: plus ezetimibe; trial; pitavastatin; standard ... See more keywords
Effect of pitavastatin and atorvastatin on regression of atherosclerosis assessed using intravascular ultrasound: a meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Coronary Artery Disease"
DOI: 10.1097/mca.0000000000000613
Abstract: Background The aim of this study is to compare the efficacy and safety of pitavastatin and atorvastatin using data from randomized-controlled trial pooled together by means of a meta-analysis and decide which is better. Methods… read more here.
Keywords: assessed using; intravascular ultrasound; pitavastatin; pitavastatin atorvastatin ... See more keywords
High Tolerability of Pitavastatin Therapy: A Case Report of Comparison with other Statins
Sign Up to like & getrecommendations! Published in 2020 at "Cardiology"
DOI: 10.1159/000506394
Abstract: Introduction: Myopathy is possibly the most clinically relevant statin-induced side effect. Case Presentation: We report a case of a 63-year-old healthy male with mixed dyslipidemia. He developed bilateral myalgia of the forearms with fluvastatin 40… read more here.
Keywords: high tolerability; case; pitavastatin; report ... See more keywords
Pitavastatin Compared with Differential Intervention Trial by Standard Therapy on Cardiovascular Events in Patients with Dyslipidemia on Chronic Hemodialysis (DIALYSIS): A Randomized Controlled Trial.
Sign Up to like & getrecommendations! Published in 2023 at "Blood purification"
DOI: 10.1159/000528763
Abstract: INTRODUCTION Statin has been reported to reduce cardiovascular events. However, the comparative efficacy of statin with standard therapy on cardiovascular events has not been sufficiently reported in patients on chronic hemodialysis. Thus, this study aimed… read more here.
Keywords: trial; therapy; group; pitavastatin ... See more keywords
Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Left Ventricular Remodeling After Acute Myocardial Infarction by Inhibiting Monocyte-Mediated Inflammation.
Sign Up to like & getrecommendations! Published in 2017 at "International heart journal"
DOI: 10.1536/ihj.16-457
Abstract: Left ventricular (LV) remodeling after myocardial infarction (MI) causes heart failure. Although medical therapies including angiotensin converting enzyme inhibitors show inhibitory effects on post-infarct LV remodeling, the prognosis of patients with post-infarct heart failure is… read more here.
Keywords: monocytes macrophages; pitavastatin nps; heart; pitavastatin ... See more keywords