Multi-omics study reveals gut microbiota dysbiosis and tryptophan metabolism alterations in GH-PitNET progression
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DOI: 10.1038/s41598-025-07812-x
Abstract: Growth hormone-secreting pituitary neuroendocrine tumors (GH-PitNETs) arise from the anterior pituitary gland and constitute 20–30% of all PitNETs, representing a significant subset of functional pituitary tumors. Despite their prevalence, the precise mechanisms underlying the development… read more here.
Keywords: pitnet patients; microbiota dysbiosis; gut microbiota; dysbiosis ... See more keywords
Case Report: Micro-RNAs in Plasma From Bilateral Inferior Petrosal Sinus Sampling and Peripheral Blood From Corticotroph Pituitary Neuroendocrine Tumors
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DOI: 10.3389/fendo.2022.748152
Abstract: Objective Circulating miRNAs are found in bodily fluids including plasma and can serve as biomarkers for diseases. The aim of this study was to provide the first insight into the landscape of circulating miRNAs in… read more here.
Keywords: pitnet patients; inferior petrosal; acth secreting; pitnet ... See more keywords
The effect of pituitary neuroendocrine tumors on the volumes of intracranial structures
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DOI: 10.3389/fneur.2025.1585921
Abstract: Objective Pituitary Neuroendocrine Tumors (PitNETs) can cause symptoms via mass effect or hormonal imbalances. This study investigated whether PitNETs induce volumetric changes in intracranial structures and assessed the diagnostic potential of these changes. Materials and… read more here.
Keywords: pitnet patients; pituitary neuroendocrine; effect; intracranial structures ... See more keywords
Genome wide analysis of circulating miRNAs in growth hormone secreting pituitary neuroendocrine tumor patients’ plasma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.894317
Abstract: Background Circulating plasma miRNAs have been increasingly studied in the field of pituitary neuroendocrine tumor (PitNET) research. Our aim was to discover circulating plasma miRNAs species associated with growth hormone (GH) secreting PitNETs versus assess… read more here.
Keywords: pitnet patients; mir 625; patients plasma; pitnet ... See more keywords