Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy
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DOI: 10.1002/pro.3380
Abstract: Here we report the enzymologic characterization of recombinant human pitrilysin metallopeptidase 1 (Pitrm1) and derivative mutants including the arginine‐to‐glutamine substitution mutant Pitrm1 R183Q, which has been implicated in inherited amyloidogenic neuropathy. Recombinant Pitrm1 R183Q was… read more here.
Keywords: pitrm1 r183q; human pitrilysin; amyloidogenic neuropathy; requirement ... See more keywords