Articles with "pitstop" as a keyword



Inhibition Clathrin Mediated Endocytosis: Pitstop 1 and Pitstop 2 Chimeras

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Published in 2024 at "ChemMedChem"

DOI: 10.1002/cmdc.202400253

Abstract: Twenty‐five chimera compounds of Pitstop 1 and 2 were synthesised and screened for their ability to block the clathrin terminal domain‐amphiphysin protein‐protein interaction (NTD‐PPI using an ELISA) and clathrin mediated endocytosis (CME) in cells. Library… read more here.

Keywords: pitstop; clathrin mediated; ppi inhibition; mediated endocytosis ... See more keywords