Safety of Withholding Perioperative Hydrocortisone for Patients With Pituitary Adenomas With an Intact Hypothalamus-Pituitary-Adrenal Axis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.42221
Abstract: Key Points Question Is withholding hydrocortisone during the perioperative period of pituitary adenoma surgery noninferior to the conventional regimen of hydrocortisone supplementation for patients with an intact hypothalamus-pituitary-adrenal (HPA) axis, who account for more than… read more here.
Keywords: patients pituitary; pituitary adenomas; axis; perioperative hydrocortisone ... See more keywords
Pituitary adenomas in children and young adults
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DOI: 10.1007/s00381-018-3853-3
Abstract: PurposePituitary adenomas are rare in the pediatric population. We present a recent cohort of children operated transsphenoidally on pituitary adenoma from a single center.MethodsInclusion criteria were age 1cm3). Time from onset of symptoms to first operation… read more here.
Keywords: children young; surgery; transsphenoidal surgery; pituitary adenomas ... See more keywords
Early recognition of aggressive pituitary adenomas: a single-centre experience
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3396-5
Abstract: BackgroundPituitary adenomas are usually considered benign tumours, although some of them can exhibit an aggressive behaviour. Patients with clinically aggressive pituitary adenomas are frequently diagnosed with larger masses, and may present an earlier recurrence (or… read more here.
Keywords: adenoma; medical treatment; aggressive pituitary; pituitary adenoma ... See more keywords
Ki-67 labeling index and expression of p53 are non-predictive for invasiveness and tumor size in functional and nonfunctional pituitary adenomas
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-019-03879-4
Abstract: BackgroundIt is still controversial whether an increased proliferation index is correlated with the tumor invasiveness of pituitary adenomas. A homogeneous large monocentric series of pituitary adenomas was retrospectively analyzed. The correlation between the proliferation indices… read more here.
Keywords: pituitary adenomas; adenomas; expression; p53 ... See more keywords
Solid tumor size for prediction of recurrence in large and giant non-functioning pituitary adenomas
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DOI: 10.1007/s10143-021-01662-7
Abstract: A subset of large non-functioning pituitary adenomas (lNFPA) and giant non-functioning pituitary adenomas (gNFPA) undergoes early progression/recurrence (P/R) after surgery. This study revealed the clinical and image predictors of P/R in lNFPA and gNFPA, with… read more here.
Keywords: non functioning; solid tumor; pituitary adenomas; functioning pituitary ... See more keywords
How to deal with giant pituitary adenomas: transsphenoidal or transcranial, simultaneous or two-staged?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2371-6
Abstract: Giant pituitary adenomas (diameter >4 cm) are a challenge to treat, and there is no consensus on the optimal surgical strategy. We report here our experience in surgical management of these lesions. Adult patients with giant… read more here.
Keywords: deal giant; giant pituitary; adenomas transsphenoidal; pituitary adenomas ... See more keywords
Comprehensive analysis of the immunological landscape of pituitary adenomas: implications of immunotherapy for pituitary adenomas
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-020-03636-z
Abstract: Immunotherapies for solid tumor are gaining traction in the clinic, however, the immunological landscape of pituitary adenomas (PAs) is not well defined. In the present study, we used the RNA-seq data of PAs to investigate… read more here.
Keywords: pas; adenomas; pituitary adenomas; immunological landscape ... See more keywords
The journey in diagnosis and treatment, from pituitary adenoma to aggressive pituitary tumors
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DOI: 10.1007/s11154-020-09561-w
Abstract: In this special issue, eminent international experts and collaborators from several continents appraise the present landscape regarding aggressive pituitary tumors, from epidemiology and diagnosis to imaging and specific forms of treatment. Most pituitary adenomas grow… read more here.
Keywords: diagnosis; aggressive pituitary; treatment; pituitary adenomas ... See more keywords
Microsurgical therapy of pituitary adenomas
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DOI: 10.1007/s12020-017-1458-3
Abstract: PurposeWe report the efficacy and safety of transsphenoidal microsurgery in a large and homogeneous cohort of patients with pituitary adenomas (PAs) treated at a single Institute by a single neurosurgeon.MethodsA total of 2145 consecutive patients… read more here.
Keywords: cushing disease; microsurgical therapy; tsh secreting; pituitary adenomas ... See more keywords
Comment on Microsurgical therapy of pituitary adenomas
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DOI: 10.1007/s12020-018-1558-8
Abstract: In this article [1], Mortini et al. review their extensive experience with the surgical treatment of pituitary adenomas. Their results, in terms of tumor resection and normalization rates of hormonal oversecretion are outstanding, while the… read more here.
Keywords: therapy pituitary; comment microsurgical; microsurgical therapy; pituitary adenomas ... See more keywords
Strategies to reduce readmissions for hyponatremia after transsphenoidal surgery for pituitary adenomas
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1656-7
Abstract: PurposeDisorders of water balance, particularly hyponatremia from altered antidiuretic hormone (ADH) secretion, are a common post-operative complication of transsphenoidal surgery (TSS). We present our results from implementation of a 2-week 1.5 liter/daily fluid restriction on… read more here.
Keywords: fluid restriction; transsphenoidal surgery; pituitary adenomas; hyponatremia ... See more keywords