The causes and consequences of pituitary gigantism
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-018-0114-1
Abstract: In the general population, height is determined by a complex interplay between genetic and environmental factors. Pituitary gigantism is a rare but very important subgroup of patients with excessive height, as it has an identifiable… read more here.
Keywords: diagnosis; insulin like; growth hormone; gigantism ... See more keywords
Chromosomal microdeletion leading to pituitary gigantism through hormone-gene overexpression.
Sign Up to like & getrecommendations! Published in 2023 at "Human molecular genetics"
DOI: 10.1093/hmg/ddad053
Abstract: Pituitary gigantism is a rare endocrinopathy characterized by tall stature due to growth hormone (GH) hypersecretion. This condition is generally linked to a genetic predisposition to tumors that produce GH or GH-releasing hormone (GHRH). Here,… read more here.
Keywords: pituitary gigantism; hormone; overexpression; microdeletion ... See more keywords
Efficacy and safety of long-acting pasireotide in Japanese patients with acromegaly or pituitary gigantism: results from a multicenter, open-label, randomized, phase 2 study.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine journal"
DOI: 10.1507/endocrj.ej16-0624
Abstract: A multicenter, open-label, phase 2 study was conducted to investigate the efficacy and safety of long-acting pasireotide formulation in Japanese patients with acromegaly or pituitary gigantism. Medically naïve or inadequately controlled patients (on somatostatin analogues… read more here.
Keywords: acromegaly pituitary; patients acromegaly; open label; pituitary gigantism ... See more keywords