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   Articles with "pituitary neuroendocrine" as a keyword



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A potential impact of SARS-CoV-2 on pituitary glands and pituitary neuroendocrine tumors

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recommendations! Published in 2021 at "Endocrine"

DOI: 10.1007/s12020-021-02697-y

Abstract: Angiotensin-converting enzyme 2 (ACE2) is the receptor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The effects of SARS-CoV-2 on normal pituitary glands function or pituitary neuroendocrine tumors (PitNETs) have not yet been elucidated. Thus,… read more here.

Keywords: potential impact; pituitary neuroendocrine; pituitary glands; neuroendocrine tumors ... See more keywords

The benign-malignant paradigm in pituitary neuroendocrine tumors and the metaphor of the semaphore: Reflections of a pathologist.

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recommendations! Published in 2019 at "Endocrinologia, diabetes y nutricion"

DOI: 10.1016/j.endinu.2018.10.003

Abstract: Pituitary neuroendocrine tumors are tumors that have no specific molecular characteristics that may be applied in the context of routine clinical diagnosis. In pathology, historically (and to date) we have divided tumors into benign and… read more here.

Keywords: malignant paradigm; neuroendocrine tumors; pituitary neuroendocrine; benign malignant ... See more keywords
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A practical algorithm to predict postsurgical recurrence and progression of pituitary neuroendocrine tumours (PitNET)s

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recommendations! Published in 2020 at "Clinical Endocrinology"

DOI: 10.1111/cen.14197

Abstract: Pituitary neuroendocrine tumours (PitNET)s can be aggressive, thus presenting local invasion, postsurgical recurrence and/or resistance to treatment, responsible for significant morbidity. The study aimed at identifying prognostic factors of postsurgical outcome using data‐driven classification of… read more here.

Keywords: neuroendocrine tumours; tumours pitnet; postsurgical recurrence; pituitary neuroendocrine ... See more keywords
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Unveiling the identities of null cell tumours: Epigenomics corroborate subtle histological cues in pituitary neuroendocrine tumour/adenoma classification

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recommendations! Published in 2022 at "Neuropathology and Applied Neurobiology"

DOI: 10.1111/nan.12870

Abstract: Pituitary neuroendocrine tumour (PitNET)/adenoma classification is based on cell lineage and requires immunopositivity for adenohypophysial hormones and/or transcription factors (TFs) steroidogenic factor 1 (SF1), T‐box transcription factor TBX19 (TPIT) or pituitary‐specific positive transcription factor 1… read more here.

Keywords: null cell; cell tumours; adenoma classification; pituitary neuroendocrine ... See more keywords
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Whole exome sequencing reveals novel risk genes of pituitary neuroendocrine tumors

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recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0265306

Abstract: Somatic genetic alterations in pituitary neuroendocrine tumors (PitNET) tissues have been identified in several studies, but detection of overlapping somatic PitNET candidate genes is rare. We sequenced and by employing multiple data analysis methods studied… read more here.

Keywords: somatic variants; pitnet; neuroendocrine tumors; pituitary neuroendocrine ... See more keywords
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The molecular biology of thyrotroph pituitary neuroendocrine tumors.

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recommendations! Published in 2023 at "Endocrine journal"

DOI: 10.1507/endocrj.ej22-0514

Abstract: Pituitary neuroendocrine tumors (PitNETs), which were formerly known as pituitary adenomas, are classified in 5th Edition of the WHO Classification of Endocrine and Neuroendocrine Tumors. Since thyrotroph PitNETs are rare PitNETs, most previous studies about… read more here.

Keywords: pituitary neuroendocrine; neuroendocrine tumors; thyrotroph pitnet; biology ... See more keywords
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The World Health Organization classifications of pituitary neuroendocrine tumours: a clinico-pathological appraisal.

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recommendations! Published in 2023 at "Endocrine-related cancer"

DOI: 10.1530/erc-23-0021

Abstract: The classification of tumours of the pituitary gland has recently been revised in the 2021 5th edition World Health Organization (WHO) Classification of Central Nervous System Tumours (CNS5) and 2022 5th edition WHO Classification of… read more here.

Keywords: health organization; classification; neuroendocrine tumours; world health ... See more keywords
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Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.1056327

Abstract: Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology. Pseudocapsule has been proposed as the… read more here.

Keywords: pseudocapsule; neuroendocrine tumors; pseudocapsule based; based extracapsular ... See more keywords
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Clinical, hormonal and pathomorphological markers of somatotroph pituitary neuroendocrine tumors predicting the treatment outcome in acromegaly

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.957301

Abstract: Background Transsphenoidal adenomectomy (TSS) of somatotroph pituitary neuroendocrine tumor (PitNET) is the first-line treatment of acromegaly. Pharmacological treatment is recommended if surgery is contraindicated or did not lead to disease remission. The choice of treatment… read more here.

Keywords: somatotroph pituitary; endocrinology; treatment outcome; pituitary neuroendocrine ... See more keywords
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Molecular characterization of epithelial-mesenchymal transition and medical treatment related-genes in non-functioning pituitary neuroendocrine tumors

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recommendations! Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1129213

Abstract: Introduction Different medical therapies have been developed for pituitary adenomas. However, Non-Functioning Pituitary Neuroendocrine Tumors (NF-PitNET) have shown little response to them. Furthermore, epithelial-mesenchymal transition (EMT) has been linked to resistance to medical treatment in… read more here.

Keywords: non functioning; pitnet; functioning pituitary; pituitary neuroendocrine ... See more keywords
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Immunotherapy for Aggressive and Metastatic Pituitary Neuroendocrine Tumors (PitNETs): State-of-the Art

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recommendations! Published in 2022 at "Cancers"

DOI: 10.3390/cancers14174093

Abstract: Simple Summary The treatment of aggressive and metastatic pituitary neuroendocrine tumors (PitNETs) refractory to current therapies, including temozolomide, is challenging and hopes are relying on personalized therapies. Immunotherapy based on immune checkpoint inhibitors (ICIs) is… read more here.

Keywords: tumors pitnets; neuroendocrine tumors; aggressive metastatic; pituitary neuroendocrine ... See more keywords