Hypothalamic–pituitary–thyroid (HPT) axis functioning in anxiety disorders. A systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Depression and Anxiety"
DOI: 10.1002/da.22692
Abstract: Depression has repeatedly been linked to subclinical hypothyroidism, and thyroid hormones have successfully been used to augment antidepressant treatment. By contrast, the extent of thyroid dysfunction in anxiety disorders remains less clear. This is surprising,… read more here.
Keywords: hpt; anxiety; hypothalamic pituitary; anxiety disorders ... See more keywords
Evaluation of hypothalamus‐pituitary‐thyroid axis function by chronic perchlorate exposure in male rats
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22509
Abstract: Perchlorate is a widespread endocrine disruptor that was previously correlated with increased serum TSH levels and decreased thyroid hormones production both in animals and humans. Even so, the regulation of gene/protein expression in the hypothalamus,… read more here.
Keywords: pituitary thyroid; hypothalamus pituitary; perchlorate; perchlorate exposure ... See more keywords
Effect of Intracerebroventricular Administration of Apelin-13 on the Hypothalamus–Pituitary–Thyroid Axis and Peripheral Uncoupling Proteins
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-017-9638-9
Abstract: Apelin, a ligand for G protein-coupled APJ receptor, is a peptide hormone. Although apelin and APJ receptors are determined in hypothalamus and thyroid gland its role in the hypothalamus–pituitary–thyroid (HPT) axis and mechanism of action… read more here.
Keywords: apelin; group; hpt axis; hypothalamus pituitary ... See more keywords
Citrus flavanones mildly interfere with pituitary-thyroid axis in old-aged male rats.
Sign Up to like & getrecommendations! Published in 2017 at "Acta histochemica"
DOI: 10.1016/j.acthis.2017.02.005
Abstract: Citrus flavanones naringenin (NAR) and hesperetin (HES) are potent antioxidants that may contribute to maintenance of health at old age by improving cardiovascular and metabolic status. However, they may also affect thyroid hormone economy. Keeping… read more here.
Keywords: old aged; thyroid axis; pituitary thyroid; citrus flavanones ... See more keywords
Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.07.038
Abstract: Endocrine disruptors (EDs), chemical substances widely used in industry and ubiquitously distributed in the environment, are able to interfere with the synthesis, release, transport, metabolism, receptor binding, action, or elimination of endogenous hormones. EDs affect… read more here.
Keywords: disruption; thyroid axis; hypothalamus pituitary; pituitary thyroid ... See more keywords
Photoperiodic regulation of pituitary thyroid-stimulating hormone and brain deiodinase in Atlantic salmon
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111056
Abstract: Seasonal timing is important for many critical life history events of vertebrates, and photoperiod is often used as a reliable seasonal cue. In mammals and birds, it has been established that a photoperiod-driven seasonal clock… read more here.
Keywords: thyroid stimulating; hormone; stimulating hormone; salmon ... See more keywords
Disruption of the hypothalamic‐pituitary‐thyroid axis on co‐exposures to dithiocarbamate and neonicotinoid pesticides: Study in a wildlife bird, Amandava amandava
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2017.02.010
Abstract: HIGHLIGHTSLow dose exposure to imidacloprid and mancozeb disrupt the avian HPT axis.Decreased epithelial cell heights and N/C ratio suggest the inactivity of follicles.Hormones of the pituitary‐thyroid axis revealed disruption of the HPT axis.Cumulative toxicity reflected… read more here.
Keywords: amandava; disruption; axis; thyroid axis ... See more keywords
Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.12.029
Abstract: Bisphenol A (BPA) is a component of polycarbonate plastics, epoxy resins and polystyrene found in many common products. Several reports revealed potent in vivo and in vitro effects. In this study we analyzed the effects… read more here.
Keywords: bpa; thyroid axis; hypothalamic pituitary; pituitary thyroid ... See more keywords
The impact of combination therapy with metformin and exogenous vitamin D on hypothalamic‐pituitary‐thyroid axis activity in women with autoimmune thyroiditis and high‐normal thyrotropin levels
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13233
Abstract: Metformin was found to decrease thyrotropin levels in subjects with non‐autoimmune but not with autoimmune hypothyroidism. Vitamin D reduced thyroid autoimmunity without affecting thyrotropin and thyroid hormone levels. The aim of the current study was… read more here.
Keywords: exogenous vitamin; thyrotropin levels; thyrotropin; hypothalamic pituitary ... See more keywords
Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine journal"
DOI: 10.1507/endocrj.ej17-0272r
Abstract: Di-(2-ethylhexyl) phthalate (DEHP) is extensively used in many personal care and consumer products, which results in widespread human exposure. Limited studies have suggested that exposure to DEHP may affect thyroid function, but little is known… read more here.
Keywords: ethylhexyl phthalate; thyroid; pituitary thyroid; thyroid axis ... See more keywords
Sex Dimorphic Responses of the Hypothalamus-Pituitary-Thyroid Axis to Energy Demands and Stress
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.746924
Abstract: The hypothalamus-pituitary-thyroid-axis (HPT) is one of the main neuroendocrine axes that control energy expenditure. The activity of hypophysiotropic thyrotropin releasing hormone (TRH) neurons is modulated by nutritional status, energy demands and stress, all of which… read more here.
Keywords: energy; thyroid axis; hypothalamus pituitary; sex ... See more keywords