Long-term effects of somatostatin analogues in rat GH-secreting pituitary tumor cell lines
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-021-01609-1
Abstract: First-generation somatostatin analogs, octreotide (OCT) and lanreotide, are the cornerstone for the medical treatment of growth hormone (GH)-secreting pituitary tumors. A new multireceptor analog, such as pasireotide (PAS), showed better activity than OCT in long-term… read more here.
Keywords: pituitary tumor; long term; secreting pituitary; cell ... See more keywords
[Pituitary tumor resection in a patient with SARS-CoV-2 (COVID-19) infection. A case report and suggested airway management guidelines].
Sign Up to like & getrecommendations! Published in 2020 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2020.06.001
Abstract: The 2020 pandemic caused by the novel coronavirus, COVID-19, had its headquarters in China. It causes Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and presents a broad spectrum of clinical manifestations, ranging from entirely asymptomatic… read more here.
Keywords: pituitary tumor; airway management; case; management ... See more keywords
Post-Traumatic Pituitary Tumor Apoplexy After Closed Head Injury: Case Report and Review of the Literature.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.08.238
Abstract: BACKGROUND Head trauma is a rare inciting factor of pituitary apoplexy (PA); however, there is a clear temporal relationship between trauma and apoplexy, and this is the first reported case of PA after an assault.… read more here.
Keywords: head; pituitary tumor; tumor apoplexy; case ... See more keywords
The Effect of Race on Short-Term Pituitary Tumor Outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.01.241
Abstract: BACKGROUND The relationship between race and neurosurgical outcomes is poorly characterized despite its importance. The influence of race on short-term patient outcomes, in a pituitary tumor surgery population, was assessed. METHODS Coarsened exact matching was… read more here.
Keywords: race; significant difference; pituitary tumor; race short ... See more keywords
Acute hypopituitarism associated with periorbital swelling and cardiac dysfunction in a patient with pituitary tumor apoplexy: a case report
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-017-1371-7
Abstract: BackgroundPituitary tumor apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction in a preexisting pituitary adenoma. It typically manifests as an acute episode of headache, visual disturbance, mental status changes, cranial nerve… read more here.
Keywords: pituitary tumor; tumor apoplexy; case; cardiac dysfunction ... See more keywords
MON-466 Transcriptome Dynamics of in vitro Human Pituitary Tumor Primary Culture
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-466
Abstract: Abstract Lack of an immortalized or long-term hormone-secreting human pituitary tumor in vitro cell line has significantly hampered studies of etiopathogenesis and development of targeted therapies for pituitary tumors. Various media, vessels, substrates and additives… read more here.
Keywords: human pituitary; pituitary tumor; cell; hormone ... See more keywords
MON-470 Pharmacological Inhibition of LAT1 Suppresses Proliferation and Hormone Synthesis in Rat Pituitary Tumor GH4 Cells [cc1] Synthesis May Be Better as Only mRNAs Were Measured
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-470
Abstract: Abstract Pituitary tumors (PTs) occur in almost 17 % of the population and they represent about 10 % of all intracranial tumors. Growth hormone-producing pituitary tumors account for about 12% of pituitary tumors. At present,… read more here.
Keywords: gh4 cells; hormone; pituitary tumor; growth ... See more keywords
Atypical pituitary adenoma with MEN1 somatic mutation associated with abnormalities of DNA mismatch repair genes; MLH1 germline mutation and MSH6 somatic mutation.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine journal"
DOI: 10.1507/endocrj.ej17-0036
Abstract: The mechanism of pituitary tumorigenesis remains largely unknown. Lynch syndrome is an autosomal, dominantly inherited syndrome caused by a defective mismatch repair (MMR) mechanism involved in the development of various tumors at an early age.… read more here.
Keywords: pituitary tumor; somatic mutation; analysis; mismatch repair ... See more keywords
Connexin Expression in Pituitary Adenomas and the Effects of Overexpression of Connexin 43 in Pituitary Tumor Cell Lines
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13040674
Abstract: Gap junction intercellular communication (GJIC) is considered a key mechanism in the regulation of tissue homeostasis. GJIC structures are organized in two transmembrane channels, with each channel formed by connexins (Cxs). GJIC and Cxs expression… read more here.
Keywords: pituitary tumor; cell lines; tumor cell; expression ... See more keywords
Pituitary Tumor-Transforming Gene 1/Delta like Non-Canonical Notch Ligand 1 Signaling in Chronic Liver Diseases
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23136897
Abstract: The management of chronic liver diseases (CLDs) remains a challenge, and identifying effective treatments is a major unmet medical need. In the current review we focus on the pituitary tumor transforming gene (PTTG1)/delta like non-canonical… read more here.
Keywords: pituitary tumor; tumor transforming; liver diseases; transforming gene ... See more keywords