P2864A novel mechanism of sinus node dysfunction: intergenic deletion between PITX2 and ANK2 disrupts chromatin structure in pacemaker cell differentiation
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DOI: 10.1093/eurheartj/ehz748.1173
Abstract: Genetics of sinus node dysfunction (SND) remains poorly understood with few genes identified (HCN4, SCN5A, GJA5, KCNQ1, MYH6 and ANK2) and further genetic heterogeneity. We report two families with SND segregating with an intergenic deletion… read more here.
Keywords: intergenic deletion; deletion; sinus node; pitx2 ank2 ... See more keywords