Crystal structures reveal that the sterically hindered pivaloyl‐cisProlyl amide bond is energetically frustrated
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DOI: 10.1002/pep2.24337
Abstract: CisPro/transPro isomerism at the prolyl amide bond is a fundamental dynamism governing protein folding, structure, and functions. Since cisPro crystal structures are rare, the interactions influencing their structures are less understood, unlike transPro. Crystal data… read more here.
Keywords: pivaloyl cisprolyl; sterically hindered; amide bond; hindered pivaloyl ... See more keywords